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Importantly, these receptors ended up identified to happen to be activated by a wide array of endogenous opioids at a focus comparable to that observed for activation and signaling of classical opiate receptors. Subsequently, these receptors were found to possess scavenging action, binding to and lowering endogenous amounts of opiates readily avail

Importantly, these receptors have been discovered to are actually activated by an array of endogenous opioids in a concentration just like that noticed for activation and signaling of classical opiate receptors. Consequently, these receptors have been discovered to obtain scavenging activity, binding to and lowering endogenous levels of opiates rea